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Tirzepatide Pharma
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Purification Services

Your Partner for Clinical Peptide Services

Ensuring the effective purification of your Peptide API is fundamental to a successful scale-up process, an efficient commercialization plan, and a secure supply chain. Our purification services span a wide range of scales (from grams to multi 100 kgs), and phases (from Phase 1 to commercial manufacturing).

With an extensive range of solutions, including reverse and normal phase preparative chromatography, Supercritical Fluid Chromatography (SFC), and Tangential Flow Filtration (TFF), we work with you to tailor an optimal purification program based on your objectives and goals, at every stage of the drug development cycle.

Normal Phase

Reverse Phase

Reverse Phase

 

Our normal phase chromatography capabilities allow the isolation of an impurity down to milligram levels, enabling the large-scale purification (100s of kilograms) of an intermediate or API from a multi-step synthesis in up to 40 cm diameter columns.

Benefit from our cross-functional experience in chromatography, analytics and cGMP production, supported by our dedicated project management team.

Reverse Phase

Reverse Phase

Reverse Phase

 

For reverse phase chromatography, our capabilities allow the isolation of an impurity down to milligram levels, enabling the large-scale purification (100s of kilograms) of an intermediate or API from a multi-step synthesis in up to 100 cm diameter columns.

Our experienced team of purification experts bring many years of cross-functional experience in chromatography, analytics and cGMP production to your project, supported by our dedicated project management team.

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography

 

Our cutting-edge Supercritical Fluid Chromatography (SFC) purification capabilities span from small-scale development through to multi-100 kg commercial production in up to 23 cm diameter columns, while also enabling the efficient management of your product’s environmental impact.

Your project will benefit from our cross-functional purification team of experts, each with many years of experience in chromatography, analytics and cGMP production, supported by our dedicated project management team.

Tangential Flow

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography

 

Our Tangential Flow Filtration (TFF) capabilities allow the isolation of an impurity down to milligram levels, enabling the large-scale purification (100s of kilograms) of an intermediate or API from a multi-step synthesis in up to 6m2 filter membranes.

Supported by our dedicated project management team, your project will benefit from our purification team of experts, each with many years of cross-functional experience in tangential flow, analytics and cGMP production.

Our Commitment to Quantity Peptide Synthesis

Chromatography is a major consumer of solvents, so when considering your process and its environmental footprint, large-scale chromatography can be a limiting factor. We have taken a proactive approach to improving this challenge with massive investment in Supercritical Fluid Chromatography (SFC).

From small-scale development through to multi-100 kg commercial production, our expanded SFC capabilities enable the efficient management of your product’s environmental impact. When SFC cannot be used, we implement the reuse and recycling of solvents as an alternative.

Want to find out more?

 Get in touch with our team of experts to explore bespoke end-to-end CDMO support of your complete drug lifecycle
at any scale. 

Get in Touch
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USA Bachem Pharma

17250 Dallas Parkway, Dallas, TX, USA

1-866-935-5383

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